Clinical research networks and assessing pandemic severity

Assessing cough severity and efficacy of therapy in clinical research: ACCP evidence-based clinical practice guidelines.

OBJECTIVES To review the literature on identifying cough and to make evidence-based recommendations for assessing the efficacy of cough-modifying agents in clinical research. DESIGN/METHODOLOGY Ovid MEDLINE literature review (through March 2004) for all studies published in the English language since 1953 using the medical subject heading terms "assessing the impact of cough," "assessing the ...

Assessing and Managing the Risks of Potential Pandemic Pathogen Research

The ongoing controversy surrounding highly pathogenic avian influenza virus research has generated considerable discussion among virologists, public health researchers, and biosafety/biosecurity experts (1–3). The most recent pause in research instituted by the U.S. Office of Science and Technology Policy calls for an independently performed risk-benefit analysis (RBA) to be completed within a ...

Research and Clinical Applications of Assessing Balance

Returning athletes to competition following injury often creates a dilemma for athletic trainers and team physicians. Most clinicians gather as much data as possible before deciding whether to return an athlete to competition following injury. The status of the postural control system and balance is important for certain pathologies and therefore should be considered in these clinical decisions...

Clinical research ethics for critically ill patients: a pandemic proposal.

Pandemic H1N1 influenza is projected to be unprecedented in its scope, causing acute critical illness among thousands of young otherwise healthy adults, who will need advanced life support. Rigorous, relevant, timely, and ethical clinical and health services research is crucial to improve their care and outcomes. Studies designed and conducted during a pandemic should be held to the same high m...

Avian influenza: assessing the pandemic threat Avian influenza: assessing the pandemic threat